Grant
Title | Due Date | Maximum Award Amount Sort descending | Description |
---|---|---|---|
ROSES 2023: B.10 Heliophysics Flight Opportunities Studies | Varies | Proposers must retrieve the instructions document (zip file) associated with the application package for this opportunity as there is at least one required form that must be attached to the submitted proposal package. The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) – 2023 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 14, 2023. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology in space and Earth sciences supported by SMD. Awards will be made as grants, cooperative agreements, contracts, and inter- or intra-agency transfers, depending on the nature of the work proposed, the proposing organization, and/or program requirements. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables 2 and 3), a table that provides a very top level summary of proposal contents (Table 1), and the full text of the ROSES-2023 "Summary of Solicitation", may all be found NSPIRES at http://solicitation.nasaprs.com/ROSES2023. This synopsis is associated with one of the individual program elements within ROSES, but this is a generic summary that is posted for all ROSES elements. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of this NRA at http://solicitation.nasaprs.com/ROSES2023table2 and http://solicitation.nasaprs.com/ROSES2023table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in The Lunar Data Analysis Program (NNH23ZDA001N-LDAP) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on “C.8 Lunar Data Analysis (.pdf)” to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read “C.1 Planetary Science Research Program Overview (.pdf)” from that same page. While the letters and numbers are different for each element within ROSES (A.12, B.7, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview. Frequently asked questions for ROSES are posted at http://science.nasa.gov/researchers/sara/faqs. Questions concerning general ROSES-2023 policies and procedures may be directed to Max Bernstein, Lead for Research, Science Mission Directorate, at sara@nasa.gov, but technical questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: http://science.nasa.gov/researchers/sara/program-officers-list. Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at http://nspires.nasaprs.com and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2023 blog feed for amendments, clarifications, and corrections to at http://science.nasa.gov/researchers/sara/grant-solicitations/ROSES-2023, and (3) The ROSES-2023 due date Google calendars (one for each science division). Instructions are at https://science.nasa.gov/researchers/sara/library-and-useful-links (link from the words due date calendar). https://www.grants.gov/web/grants/view-opportunity.html?oppId=346061 |
|
ROSES 2023: C.14 Planetary Science and Technology Through Analog Research | Varies | The close date above is the date for the Step-1 proposal submission. See the solicitation for the Step-2 due date. Step-2 proposals cannot be submitted if a Step-1 proposal was not submitted. Proposers must retrieve the instructions document (zip file) associated with the application package for this opportunity as there is at least one required form that must be attached to the submitted proposal package. The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) – 2023 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 14, 2023. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology in space and Earth sciences supported by SMD. Awards will be made as grants, cooperative agreements, contracts, and inter- or intra-agency transfers, depending on the nature of the work proposed, the proposing organization, and/or program requirements. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables 2 and 3), a table that provides a very top level summary of proposal contents (Table 1), and the full text of the ROSES-2023 "Summary of Solicitation", may all be found NSPIRES at http://solicitation.nasaprs.com/ROSES2023. This synopsis is associated with one of the individual program elements within ROSES, but this is a generic summary that is posted for all ROSES elements. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of this NRA at http://solicitation.nasaprs.com/ROSES2023table2 and http://solicitation.nasaprs.com/ROSES2023table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in The Lunar Data Analysis Program (NNH23ZDA001N-LDAP) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on “C.8 Lunar Data Analysis (.pdf)” to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read “C.1 Planetary Science Research Program Overview (.pdf)” from that same page. While the letters and numbers are different for each element within ROSES (A.12, B.7, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview. Frequently asked questions for ROSES are posted at http://science.nasa.gov/researchers/sara/faqs. Questions concerning general ROSES-2023 policies and procedures may be directed to Max Bernstein, Lead for Research, Science Mission Directorate, at sara@nasa.gov, but technical questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: http://science.nasa.gov/researchers/sara/program-officers-list. Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at http://nspires.nasaprs.com and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2023 blog feed for amendments, clarifications, and corrections to at http://science.nasa.gov/researchers/sara/grant-solicitations/ROSES-2023, and (3) The ROSES-2023 due date Google calendars (one for each science division). Instructions are at https://science.nasa.gov/researchers/sara/library-and-useful-links (link from the words due date calendar). https://www.grants.gov/web/grants/view-opportunity.html?oppId=346072 |
|
ROSES 2023: C.12 Planetary Instrument Concepts for the Advancement of Solar System Observations | Varies | This program element does not have a proposal due date. Proposals may be submitted at any time, pending certain eligibility timing issues related to resubmissions and duplicate proposal avoidance, see the program element text and appropriate overview appendix (e.g., B.1 or C.1). The date shown of 3/29/2024 is the last day that proposals may be submitted subject to the ROSES-23 rules and the current Guidebook for Proposers. The ROSES-24 version of this program element is planned to overlap with this ROSES-23 version by a few weeks, allowing continuous submission of proposals across ROSES years. Proposers must retrieve the instructions document (zip file) associated with the application package for this opportunity as there is at least one required form that must be attached to the submitted proposal package. The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) – 2023 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 14, 2023. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology in space and Earth sciences supported by SMD. Awards will be made as grants, cooperative agreements, contracts, and inter- or intra-agency transfers, depending on the nature of the work proposed, the proposing organization, and/or program requirements. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables 2 and 3), a table that provides a very top level summary of proposal contents (Table 1), and the full text of the ROSES-2023 "Summary of Solicitation", may all be found NSPIRES at http://solicitation.nasaprs.com/ROSES2023. This synopsis is associated with one of the individual program elements within ROSES, but this is a generic summary that is posted for all ROSES elements. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of this NRA at http://solicitation.nasaprs.com/ROSES2023table2 and http://solicitation.nasaprs.com/ROSES2023table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in The Lunar Data Analysis Program (NNH23ZDA001N-LDAP) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on “C.8 Lunar Data Analysis (.pdf)” to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read “C.1 Planetary Science Research Program Overview (.pdf)” from that same page. While the letters and numbers are different for each element within ROSES (A.12, B.7, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview. Frequently asked questions for ROSES are posted at http://science.nasa.gov/researchers/sara/faqs. Questions concerning general ROSES-2023 policies and procedures may be directed to Max Bernstein, Lead for Research, Science Mission Directorate, at sara@nasa.gov, but technical questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: http://science.nasa.gov/researchers/sara/program-officers-list. Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at http://nspires.nasaprs.com and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2023 blog feed for amendments, clarifications, and corrections to at http://science.nasa.gov/researchers/sara/grant-solicitations/ROSES-2023, and (3) The ROSES-2023 due date Google calendars (one for each science division). Instructions are at https://science.nasa.gov/researchers/sara/library-and-useful-links (link from the words due date calendar). https://www.grants.gov/web/grants/view-opportunity.html?oppId=346103 |
|
Communications, Circuits, and Sensing-Systems | No Due Date Given | Varies | The Communications, Circuits, and Sensing-Systems (CCSS) Program supports innovative research in circuit and system hardware and signal processing techniques. CCSS also supports system and network architectures for communications and sensing to enable the next-generation cyber-physical systems (CPS) that leverage computation, communication, and sensing integrated with physical domains. CCSS invests in micro- and nano-electromechanical systems (MEMS/NEMS), physical, chemical, and biological sensing systems, neurotechnologies, and communication & sensing circuits and systems. The goal is to create new complex and hybrid systems ranging from nano- to macro-scale with innovative engineering principles and solutions for a variety of applications including but not limited to healthcare, medicine, environmental and biological monitoring, communications, disaster mitigation, homeland security, intelligent transportation, manufacturing, energy, and smart buildings. CCSS encourages research proposals based on emerging technologies and applications for communications and sensing such as high-speed communications of terabits per second and beyond, sensing and imaging covering microwave to terahertz frequencies, personalized health monitoring and assistance, secured wireless connectivity and sensing for the Internet of Things, and dynamic-data-enabled autonomous systems through real-time sensing and learning. Areas managed by CCSS Program Directors (please contact Program Directors listed in the CCSS staff directory for areas of interest): RF Circuits and Antennas for Communications and Sensing RF Communications and Sensing Technologies from kHz to THz Antennas and Wave Propagation for Communications and Sensing Circuits and Systems for Secured Communications and Sensing Trusted Microelectronic Circuits RF Biomedical Applications and Remote Sensing Bio-mimetic Circuits and Systems Dynamic-data-enabled Reconfigurable RF Subsystems through Sensing and Machine Learning Wireless Energy Transfer and RF Energy Harvesting Communication Systems and Signal Processing Wireless, Optical, and Hybrid Communications and Networking Full-duplex, massive MIMO, mm-Wave, and THz communications Spectrum Access and Sharing Integrated Sensing, Communication, and Computational Systems Signal Processing, image processing, and Compressive Sampling Cyber Physical Systems and Hardware-controlled Secured Communications Dynamic-data-enabled Communication Systems through Sensing and Machine Learning Quantum Communication Systems Dynamic Bio-Sensing Systems Micro, Nano, and Bio Systems (MEMS/NEMS) Chemical, Biological, and Physical Diagnostics Sensors, Actuators, and Electronic Interfaces Ultra-Low Power Wearable and Implantable Sensing Systems Dynamic-data-enabled Reconfigurable Sensing Systems Personalized Health Monitoring Systems through Sensing and Machine Learning Neuroengineering and Brain-Inspired Concepts and Designs https://www.grants.gov/web/grants/view-opportunity.html?oppId=346204 |
Advancing Integrated Models (AIM) of Care to Improve Pregnancy Outcomes among Women Who Experience Persistent Disparities (R01 Clinical Trial Optional) | Varies | Disparities in maternal health outcomes is a public health crisis that requires new insights and solutions. The purpose of this initiativeadvancing integrated models (AIM) of careis to stimulate research to develop or evaluate supportive care models that address healthcare access or healthcare quality together with structural or social inequities in order to prevent adverse maternal health outcomes among racial and ethnic minority women. This includes original intervention research and research evaluating the impact of federal, tribal, state, local, or organizational policies and programs on maternal health outcomes. Outcomes of interest include pregnancy-related morbidity (e.g., hypertension, diabetes, obesity, cerebrovascular disease, mental illness) including severe maternal morbidity; pregnancy-associated factors (e.g., violence exposure including firearm violence, substance use disorders, dietary patterns), and maternal mortality. https://www.grants.gov/web/grants/view-opportunity.html?oppId=346439 |
|
Ovarian Cancer Clinical Trial Award | Varies | The OCRP Clinical Trial Award supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of ovarian cancer. Clinical trials may be designed to evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance, and/or emerging approaches and technologies. Proposed projects may range from small proof-of-concept trials (e.g., pilot, first in human, phase 0) to demonstrate the feasibility or inform the design of more advanced trials through large-scale trials to determine efficacy in relevant patient populations. https://www.grants.gov/web/grants/view-opportunity.html?oppId=346665 |
|
Office of Elementary and Secondary Education (OESE): Well-Rounded Education Programs: Innovative Approaches to Literacy (IAL) Program, Assistance Listing Number 84.215G | Varies | Note: Each funding opportunity description is a synopsis of information in the Federal Register application notice. For specific information about eligibility, please see the official application notice. The official version of this document is the document published in the Federal Register. Free Internet access to the official edition of the Federal Register and the Code of Federal Regulations is available on GPO Access at: http://www.access.gpo.gov/nara/index.html. Please review the official application notice for pre-application and application requirements, application submission information, performance measures, priorities and program contact information. For the addresses for obtaining and submitting an application, please refer to our Revised Common Instructions for Applicants to Department of Education Discretionary Grant Programs, published in the Federal Register on December 7, 2022. Purpose of Program: The IAL program supports high-quality programs designed to develop and improve literacy skills for children and students from birth through 12th grade in high-need local educational agencies (LEAs) and schools. IAL promotes innovative literacy programs that support the development of literacy skills in low-income communities, including programs that (1) develop and enhance effective school library programs, which may include providing professional development for school librarians, books, and up-to-date materials to high-need schools; (2) provide early literacy services, including pediatric literacy programs through which, during well-child visits, medical providers trained in research-based methods of early language and literacy promotion provide developmentally appropriate books and recommendations to parents to encourage them to read aloud to their children starting in infancy; and (3) provide high-quality books on a regular basis to children and adolescents from low-income communities to increase reading motivation, performance, and frequency. Assistance Listing Number (ALN) 84.215G. https://www.grants.gov/web/grants/view-opportunity.html?oppId=346715 |
|
Fluid Dynamics | No Due Date Given | Varies | TheFluid Dynamicsprogram is part of the Transport Phenomena cluster, which also includes 1) theCombustion and Fire Systemsprogram; 2) theParticulate and Multiphase Processesprogram; and 3) theThermal Transport Processesprogram. TheFluid Dynamicsprogram supports fundamental research toward gaining an understanding of the physics of various fluid dynamics phenomena. Proposed research should contribute to basic scientific understanding using and/or creating innovative experimental, theoretical, and/or computational methods. Major areas of interest and activity in the program include: ·Turbulence and transition: High Reynolds number experiments; large eddy simulation; direct numerical simulation; transition to turbulence; 3-D boundary layers; separated flows; flow control; and drag reduction.High-speed boundary-layer transition and turbulence at Mach numbers greater than 5 to understand modal and/or non-modal interactions leading to boundary layer transition and the ensuing developing and fully developed turbulent boundary layer flows. ·Bio-fluid physics:Bio-inspired flows; biological flows with emphasis on flow physics. ·Non-Newtonian fluid mechanics:Viscoelastic flows; solutions of macro-molecules. ·Microfluidics and nanofluidics: Micro-and nano-scale flow physics. ·Wind and ocean energy harvesting:Focused on fundamental fluid dynamics associated with renewal energy systems or concepts. ·Fluid-structure interactions (FSI):Two-way coupled FSI applications across the low- to high-Reynolds number range are of interest to NSF. In addition, NSF-AFOSR (Air Force Office of Scientific Research) joint funding area is focused on theory, modeling and/or experiments for hypersonic applications. Proposals will be jointly reviewed by NSF and AFOSR using the NSF panel format. Actual funding format and agency split for an award will be determined after the proposal selection process. AFOSR participates in this initiative throughtheAerothermodynamics program(program officerDr. Sarah Popkin). ·Canonicalconfigurations:Experimental research is encouraged to develop spatiotemporally resolveddatabases for canonical configurations to either reaffirm historicaltheories/results or to provide data in an unexplored parameter region. Fidelity and completeness for theoretical/computational validation are key attributes of theproposed experimental data. ·Artificial intelligence (AI)/machine learning:Innovative AI ideas related to the use of machine learning and other AI approaches in fluid dynamics research are encouraged to model and control the flows.Verifying new models with canonical configurations, when appropriate, is encouraged for submission to theComputational andData-Enabled Science & Engineering(CDS&E 8084) program. ·Instrumentation and Flow Diagnostics: Instrument development for time-space resolvedmeasurements; shear stress sensors; novel flow imaging; velocimetry; etc. NOTE:Proposals that use fluid flows as a boundary input condition or a driving force in a problem do not fit within the scope of this program.Proposals focused on particulates (including droplets) two-way coupled with fluids, colloids, and multiphase rheology and processes should be directed to theParticulate andMultiphase Processesprogram (CBET PD-1415). Proposals dealing mainly with materials synthesis, processing and characterization may be more suitable for theAdvanced Manufacturingprogramin the Division of Civil, Mechanical, and Manufacturing Innovation (ENG/CMMI) orprograms in theDivision of Materials Research (MPS/DMR). Proposals focused on biological systems may be more suitable forPhysiological and Structural Systemsin the Division of Integrative Organismal Systems (BIO/IOS). INFORMATION COMMON TO MOST CBET PROGRAMS Proposals should address the novelty and/orpotentially transformative natureof the proposed work compared to previous work in the field.Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact on society and/or industry of success in the research.The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal. The duration of unsolicited proposal awards in CBET is generally up to three years. Single-investigator award budgets typically include support for one graduate student (or equivalent) and up to one month of PI time per year(awards for multiple investigator projects are typically larger). Proposal budgets that are much larger than typical should be discussed with the program director prior to submission. Proposers can view budget amounts and other information from recent awards made by this program via the "What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)" link towards the bottom of this page. Faculty Early Career Development(CAREER)program proposals are strongly encouraged.Award duration is five years.The submission deadline for Engineering CAREER proposals is in July every year. Learn more in theCAREER program description. Proposals for Conferences, Workshops, and Supplements: PIs are strongly encouraged to discuss their requests with the program director before submission of the proposal. Grants forRapid Response Research(RAPID)andEArly-concept Grants for Exploratory Research(EAGER)are also considered when appropriate.Please note that proposals of these types must be discussed with the program director before submission.Grant Opportunities for Academic Liaison with Industry (GOALI)proposals that integrate fundamental research with translational results and are consistent with the application areas of interest to each program are also encouraged. Please note that RAPID, EAGER, and GOALI proposals can be submitted anytime during the year. Details about RAPID, EAGER, and GOALI are available in the Proposal & Award Policies & Procedures Guide (PAPPG), Part 1, Chapter II, Section E: Types of Proposals. Compliance: Proposalsthat are not compliant with theProposal & Award Policies & Procedures Guide (PAPPG)will be returned without review. https://www.grants.gov/web/grants/view-opportunity.html?oppId=347020 |
DOD, Peer Reviewed Alzheimer’s, Transforming Research Award | Varies | The FY23 PRARP TRA is intended to support studies that will make transformative and advanced contributions to reduce risk of or prevent the development of AD/ADRD. Risk reduction considering TBI and/or military service is of particular interest to the program. The work should significantly accelerate efforts in AD/ADRD research and demonstrate significant positive impact toward improving patient care and/or quality of life.Key elements of this award mechanism include:• Research should be robust: The FY23 PRARP TRA mechanism is geared toward supporting robust, well designed research projects that provide significant, near-term impact on the AD/ADRD field, persons living with dementia, and their families, care-partners/caregivers, and communities. To ensure near-term applicability, inclusion of collaborative community partner approaches is strongly encouraged for all projects and is required for all projects involving clinical research.• Non-incremental advancement: Research projects should leverage existing knowledge to accelerate ideas, strengthen evidence, and move the field forward toward nearer-term impact. Projects proposing incremental advances that do not significantly propel the field are not appropriate for this mechanism.• Feedback to the community: Results and outcomes of the research supported by this mechanism must be relayed back to the community to allow for continued knowledge building.Inclusion of preliminary data is required. Use of animal models must be fully justified for relevance to human health. Clinical research applications are required to include a community collaboration research element. https://www.grants.gov/web/grants/view-opportunity.html?oppId=347146 |
|
DOD, Spinal Cord Injury, Translational Research Award | Varies | The SCIRP TRA is intended to support translational research that will accelerate the movement of promising ideas in SCI research into clinical applications. Although not all-inclusive, some examples include demonstration studies of pharmaceuticals and medical devices in preclinical systems and/or clinical research on therapeutics, devices, or practice using human tissues or resources.The ultimate goal of translational research is to move an observation forward into clinical application and accelerate the clinical introduction of health care products, technologies, or practice guidelines. Observations that drive a research idea may be derived from a laboratory discovery, population-based studies, or a clinician’s first-hand knowledge of patients and anecdotal data. However, applicants should not view translational research as a one-way continuum from bench to bedside. The research plan is encouraged to involve a reciprocal flow of ideas and information between basic and clinical science.Applicants need to clearly articulate three points along the translational research spectrum:• Where the field is now;• Where the field will be after the successful completion of the proposed research project; and• What the next step will be after completion of the proposed project.Applications must include preliminary and/or published data that are relevant to SCI and supports the proposed research project.Applications to the FY23 SCIRP TRA may include preclinical animal studies (except where otherwise specified) and/or clinical research involving human subjects and human anatomical substances. Proposal of animal studies is not a required element of this mechanism though applications including animal studies must include a clear justification for the animal model chosen including relevance to human SCI. The FY23 SCIRP TRA may also support ancillary studies that are associated with an ongoing or completed clinical trial and projects that optimize the design of future clinical trials.The FY23 SCIRP TRA also allows funding for a pilot clinical trial as PART of the funded research project where limited clinical testing of a novel intervention or device is necessary to inform the next step in the continuum of translational research. Such pilot clinical trial studies should be small, make up only a portion of the proposed Statement of Work (SOW), and be utilized to establish feasibility of a potential approach or to aid in device or intervention refinement. Alternative trial designs to traditional randomized clinical trials are allowed but should be appropriate to the objective of the trial. If a pilot clinical trial is proposed, utilization of decentralized clinical trial strategies that leverage virtual elements/tools for participant enrollment, communication, and data collection is especially encouraged. Applications that include a pilot clinical trial as part of the proposed research will have additional submission requirements and review criteria. Applications that consist entirely of a clinical trial or multiple pilot clinical trials may be administratively withdrawn. https://www.grants.gov/web/grants/view-opportunity.html?oppId=347226 |