Funding Wizard

This Funding Opportunity Announcement (FOA) is a part of NIDAs Racial Equity Initiative (REI), a multi-year, multi-pronged effort to eliminate racial inequities in NIDAs workplace, scientific workforce, and research portfolio. The purpose of this initiative is to stimulate new observational and intervention research on structural factors, organizational practices, policies, and other social, cultural, and contextual influences that lead to inequities at the intersection of HIV and substance use among underserved racial/ethnic populations affected by persistent HIV disparities. Research that addresses the multiple dimensions of individuals identity (e.g., race, ethnicity, gender, sexual orientation, gender identity) and social systems as they intersect with one another is encouraged.

The Advanced Technologies and Instrumentation for the Astronomical Sciences (ATI) program provides individual investigator and collaborative research grants for the development of new technologies and instrumentation for use in ground-based astronomy and astrophysics.The program supports achieving the science objectives of the Division of Astronomical Sciences. The development of innovative, potentially transformative, technologies and instruments are sought, even at high technical risk.Supported categories include (but are not limited to):advanced technology development, concept feasibility studies, and specialized instrumentation to enable new observations that are difficult or impossible to obtain with existing means.Proposals may include hardware and/or software development and/or analysis to enable new types of astronomical observations. Access to the ATI supported technology and instrumentation development efforts by the US astronomical community is viewed as an important metric of success. An annual Principal Investigators meeting is planned to disseminate information between the funded research efforts.

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. This Funding Opportunity Announcement (FOA) invites Exploratory/Developmental Grant applications to study the impact of opioids, alone or in combination with other substances of misuse, on placenta function and neurodevelopment during pregnancy and in the first year of life using experimental designs that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical and/or behavioral outcomes in humans to understand fundamental aspects of phenomena related to opioid exposure during pregnancy. NIH considers such studies as Basic Experimental Studies with Humans (BESH), or prospective basic science studies involving human participants that meet the NIH definition of basic research and fall within the NIH definition of clinical trials (see, e.g., NOT-OD-19-024). Applications should not propose a goal of clinical outcomes or products. Applications that propose studies including model animal research or observational studies involving humans should submit under the companion FOA, RFA-HD-23-031,"Opioid Exposure and Effects on Placenta Function, Brain Development, and Neurodevelopmental Outcomes (R21 Clinical Trials Not Allowed).

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals in the following areas of interest: Human Language Technology, computer vision, artificial intelligence, reasoning, and human-computer interaction. Proposed research should investigate innovative approaches that enable revolutionary advances in science, devices, or systems. Specifically excluded is research that primarily results in evolutionary improvements to the existing state of practice.

The Division of Atmospheric and Geospace Sciences (AGS), awards Postdoctoral Research Fellowships (PRF) to highly qualified early career investigators to carry out an independent research program. The research plan of each Fellowship must address scientific questions within the scope of AGS disciplines. These disciplines include Atmospheric Chemistry (ATC), Climate and Large-Scale Dynamics (CLD), Paleoclimate (PC), and Physical and Dynamic Meteorology (PDM) in the Atmospheric Sciences, and Aeronomy (AER), Magnetospheric Physics (MAG), Solar Terrestrial (ST), and Space Weather Research (SWR) in the Geospace Sciences. The AGS-PRF program supports researchers (also known as Fellows) for a period of up to 24 months with Fellowships that can be taken to the institution of their choice. The program is intended to recognize beginning investigators of significant potential and provide them with experiences in research that will broaden perspectives, facilitate interdisciplinary interactions, and help establish them in leadership positions within the Atmospheric and Geospace Sciences community. Fellowships are awards to individual Fellows, not institutions, and are administered by the Fellows. AGS has made it a priority to address challenges in creating an inclusive geoscience discipline through activities that increase belonging, accessibility, justice, equity, diversity, and inclusion (BAJEDI). Proposers are encouraged to explicitly address this priority in their proposed activities. Proposers who are women, veterans, persons with disabilities, and underrepresented minorities in science, technology, engineering, and mathematics (STEM), or who have attended two-year colleges and minority-serving institutions for undergraduate or graduate school, or plan to conduct their Fellowship activities at one of these institutions (e.g. Historically Black Colleges and Universities, Tribal Colleges and Universities, Hispanic Serving Institutions, Alaska Native Serving Institutions, and Hawaiian Native and Pacific Islander Serving Institutions) are especially encouraged to apply.

The FY22 BCRP Clinical Research Extension Award aims to extend the data collection, follow- up, and analysis of breast cancer clinical research studies. The intent of this mechanism is to increase the clinically relevant impact of breast cancer patient participation in clinical research by addressing the knowledge lost due to limited or early termination of patient follow-up and sample collection and analysis. The critical components of this award mechanism are: Impact: Research supported by the FY22 BCRP Clinical Research Extension Award will have the potential for a major impact and accelerate progress toward ending breast cancer. Applications are expected to identify the breast cancer patients or at-risk individuals who would ultimately benefit from the proposed research. Research Scope: Although not all-inclusive, research proposed under the FY22 BCRP Clinical Research Extension Award may entail a deeper molecular analysis of clinical samples, initiation of new correlative studies, biomarker validation, or continuing clinical follow-up of patients currently/previously enrolled in an open/ongoing or completed clinical trial. The proposed research may be hypothesis testing/generating or may be designed to generate clinically annotated and molecularly characterized experimental platforms, including patient-derived models or tissue arrays. The award may not be used to directly support a clinical trial. Feasibility: Preliminary data to support the scientific rationale and feasibility of the research approaches are required. Applications are strongly encouraged to also describe the clinical relevance of the proposed research. The applicant must demonstrate availability of, and accessibility to, the necessary resources or populations to accomplish the proposed research. Data Evaluation and Sharing: Proposed research should be based on study sample size that will ensure that the results support valid conclusions and further translation towards clinical application. It is the applicant’s responsibility to provide sufficient evidence that the sample size is appropriate to meet the study's objectives. The applicant must outline a plan to share the experimental platforms and molecular data generated from the proposed research with the scientific community. Partnering PI Option: The FY22 BCRP Clinical Research Extension Award encourages applications that include meaningful and productive collaborations between investigators. The Partnering PI Option is structured to accommodate two Principal Investigators (PIs). One PI will be identified as the Initiating PI and will be responsible for the majority of the administrative tasks associated with application submission. The other PI will be identified as a Partnering PI. The PIs may have expertise in similar or disparate scientific disciplines, but each PI is expected to bring a distinct contribution to the application; collaborations between basic science and clinical researchers are highly encouraged. Both PIs should contribute significantly to the development of the proposed research project, including the Project Narrative, Statement of Work (SOW), and other required components. The application should clearly demonstrate that both PIs have equal intellectual input into the design of the project and will devote similar and appropriate levels of effort to the conduct of the project. It is expected that funding will be balanced between both PIs unless appropriately justified. The application is expected to describe how the PIs’ unique expertise combined as a partnership will better address the research question, how the unique expertise that each individual brings to the application is critical for the research strategy and completion of the SOW, and why the work should be done together rather than through separate efforts. If recommended for funding, each PI will be named to an individual award within the recipient organization. For individual submission requirements for the Initiating and Partnering PI, refer to Section II.D.2, Content and Form of the Application Submission. Personnel: Applications are expected to include an appropriate and robust research team with the combined backgrounds and breast cancer-related expertise to enable successful conduct of the project. Consumer Advocates: Applications are required to include consumer advocate involvement. The research team must include two or more breast cancer consumer advocates, and it is the applicant’s responsibility to outline the advocates’ role in the design and execution of the study. As lay representatives, the consumer advocates must be individuals who have been diagnosed with breast cancer and are actively involved in a breast cancer advocacy organization. Their role should be independent of their employment, and they may not be employees of any organizations participating in the application. The consumer advocates should have a high level of knowledge of current breast cancer issues and the appropriate background and/or training in breast cancer research to contribute to the project. Their role should be focused on providing objective input throughout the research effort and its potential impact for individuals with, or at risk for, breast cancer.

Modification 0001: 1. Remove the requirement of the Community Benefits Plan section within the Content and Form of the Concept Paper in Section IV.C. ___________________________________________________________________________________________________________________________________ The Office of Energy Efficiency and Renewable Energy (EERE) is issuing, on behalf of the Water Power Technlogies Office (WPTO), this Funding Opportunity Announcement (FOA) titled “Bipartisan Infrastructure Law Section 41006: Water Power Projects: Innovative Technologies to Enable Low Impact Hydropower and Pumped Storage Hydropower Growth.” Awards made under this FOA will be funded, in whole or in part, with funds appropriated by the Infrastructure Investment and Jobs Act, more commonly known as the Bipartisan Infrastructure Law (BIL). This FOA seeks applications to address innovative solutions to retrofit non-powered dams with environmentally sustainable hydropower at a reasonable cost; applications to address development and testing technologies that mitigate challenges to pumped storage hydropower deployment, including market and revenue uncertainty, development costs and financing, long development timelines, permitting challenges, construction risks, and environmental impacts; and applications to address and encourage emerging organizations to support hydropower development. WPTO expects the amount of funding available for projects under this FOA will be approximately $14.5 million and cover the following topic areas: 1. Hydropower Retrofits for Non-Powered Dams; 2. Innovative Pumped Storage Hydropower Technologies; and 3. Hydropower R&D by Emerging Organizations. Please Note: In the event that an Applicant experiences technical difficulties with a submission, the Applicant should contact the eXCHANGE helpdesk for assistance (exchangehelp@hq.doe.gov). To view the complete FOA document, visit the eXCHANGE website at: https://eere-exchange.energy.gov/. Please note that you must first select this specific FOA Number in order to view the questions and answers specific to this FOA

The purpose of this funding opportunity announcement (FOA) is to solicit applications that further examine and characterize molecular underpinnings surrounding telomere status and accompanying biological pathways in response to environmental insults. Specifically, the intent is to further stimulate the field on how general telomere maintenance modulates downstream biological pathway(s) leading to cellular and organismal dysfunction. It is anticipated that proposed studies examining exposure affects at telomeric regions can actually potentiate early onset of age-related diseases. This FOA ultimately seeks to identify key mechanistic insights into telomere dynamics and how this could better dissect the interplay between environmental exposures at this vulnerable site contribute to disease (e.g., cancer, CVD, and other age-related outcomes, such as neurodegeneration).

This Funding Opportunity Announcement (FOA) invites grant applications for Environmental Health Sciences Core Centers (EHS CC). As intellectual hubs for environmental health research, the EHS CC is expected to be the thought leaders for the field and advance the goals of the NIEHS Strategic Plan (http://www.niehs.nih.gov/about/strategicplan/).The Core Centers provide critical research infrastructure, shared facilities, services and/or resources, to groups of investigators conducting environmental health sciences research.

This Funding Opportunity Announcement (FOA) solicits grant applications proposing exploratory research projects focused on the early-stage development of highly innovative technologies that improve the quality of the samples used for cancer research or clinical care. This includes new capabilities to address issues related to pre-analytical degradation of targeted analytes during the collection, processing, handling, and/or storage of cancer-relevant biospecimens. The overall goal is to support the development of highly innovative technologies capable of maximizing or otherwise interrogating the quality and utility of biological samples used for downstream analyses. This FOA will support the development of tools, devices, instrumentation, and associated methods to preserve or protect sample integrity, or establish verification criteria for quality assessment/quality control and handling under diverse conditions. These technologies are expected to accelerate and/or enhance research in cancer biology, early detection and screening, clinical diagnosis, treatment, epidemiology, or address issues associated with cancer health disparities, by reducing pre-analytical variations that affect biospecimen sample quality.This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.