Funding Wizard

The SCIRP CTRA is intended to support high-impact and/or new/emerging clinical research that may not be ready for a larger-scale clinical trial and for which feasibility/pilot studies are necessary. Projects should demonstrate potential to impact the standard of care, both immediate and long term, or contribute to evidence-based guidelines for the evaluation and care of military Service Members, Veterans, and other individuals living with SCI.• One goal of the FY23 SCIRP CTRA is to translate current and emerging techniques and interventions into the clinical space to de-risk and inform the design of more advanced trials.• Another goal is to identify the most effective diagnosis, treatment, and rehabilitation options available to support critical decision-making for patients, clinicians, care partners, and policymakers.The application should clearly articulate the scientific and strategic steps and/or preparations the research team will take during AND after the project’s period of performance to advance the research to the next stage of clinical development/implementation.The proposed studies may be interventional or observational and may involve some retrospective data analysis. Note that purely retrospective or database-related research will not be supported under this funding opportunity, some element of prospective human enrollment should be included in the project. Small/pilot clinical trials with human subjects are allowable. Alternative trial designs to traditional randomized clinical trials are allowed but should be appropriate to the objective of the trial. If a clinical trial is proposed, utilization of decentralized clinical trial strategies that leverage virtual elements/tools for participant enrollment, communication, and data collection is especially encouraged.The FY23 SCIRP CTRA differs from the FY23 SCIRP Clinical Trial Award (Funding Opportunity Number HT9425-23-SCIRP-CTA) in that the CTRA allows for the execution of both clinical research projects and clinical trials, whereas the Clinical Trial Award is restricted to the execution of clinical trials only.The FY23 CTRA differs from the FY23 SCIRP Translational Research Award (Funding Opportunity Number HT9425-23-SCIRP-TRA) in that the study proposed within an application to the FY23 SCIRP CTRA may consist entirely of a clinical trial. In contrast, if a clinical trial is proposed within a Translational Research Award application, it must make up only a portion of the project’s Statement of Work.Applications to the FY23 SCIRP CTRA mechanism must support prospective clinical research or clinical trials and may not be used for animal research. Investigators seeking support to conduct studies involving animal research should consider applying to the FY23 SCIRP Translational Research Award mechanism (Funding Opportunity Number HT9425-23-SCIRP-TRA) or FY23 SCIRP Investigator-Initiated Research Award mechanism (Funding Opportunity Number HT9425-23-SCIRP-IIRA).

The Bureau of Counterterrorism (CT) of the U.S. Department of State announces an open competition for organizations to submit applications to utilize existing Somalia Police Force (SPF) MVCP cadre to create three to four additional SPF mobile vehicle checkpoint (MVCP) teams to expand operations throughout Mogadishu intended to disrupt terrorists’ ability to use VBIEDs and to move lethal aid.

Through this funding opportunity announcement, the National Cancer Institute (NCI) intends to focus on the impacts of climate change across the cancer control continuum (R01 Clinical Trial Optional)

The SCIRP IIRA is intended to support studies that have the potential to make an important contribution to SCI research, patient care, and/or quality of life.Important aspects of this award mechanism include:• Impact: Applications should articulate the short- and long-term impact of the proposed research on both the SCI research field as well as the SCI community. Projects must address one or more of the FY23 SCIRP Focus Areas.• Relevance to Military Health: Projects should be relevant to spinal cord-injured military Service Members, Veterans, and/or their family members and care partners. Collaboration with military and VA researchers and clinicians is encouraged.• Preliminary Data: Observations that drive a research idea may be derived from laboratory discovery, population-based studies, a clinician’s first-hand knowledge of patients, or anecdotal data. Applications must include preliminary and/or published data that are relevant to the mission of the SCIRP and support the proposed research project.IIRA applications may focus on any phase of research from basic through translational, though studies focused exclusively on target identification are discouraged. Permitted research includes preclinical studies in animal models (except where otherwise specified), research with human subjects or human anatomical substances, as well as ancillary studies associated with an existing clinical trial.Clinical trials are not allowed under this funding opportunity. Applications including animal studies must have a clear justification for the animal model chosen, including relevance to human SCI.

DE-FOA-0003047, Grid Overhaul with Proactive, High-speed Undergrounding for Reliability, Resilience, and Security (GOPHURRS) To obtain a copy of the Funding Opportunity Announcement (FOA) please go to the ARPA-E website at https://arpa-e-foa.energy.gov. To apply to this FOA, Applicants must register with and submit application materials through ARPA-E eXCHANGE (https://arpa-e-foa.energy.gov/Registration.aspx). For detailed guidance on using ARPA-E eXCHANGE, please refer to the ARPA-E eXCHANGE User Guide (https://arpa-e-foa.energy.gov/Manuals.aspx). ARPA-E will not review or consider concept papers submitted through other means. For problems with ARPA-E eXCHANGE, email ExchangeHelp@hq.doe.gov (with FOA name and number in the subject line). Questions about this FOA? Check the Frequently Asked Questions available at http://arpa-e.energy.gov/faq. For questions that have not already been answered, email ARPA-E-CO@hq.doe.gov. Agency Overview: The Advanced Research Projects Agency – Energy (ARPA-E), an organization within the Department of Energy (DOE), is chartered by Congress in the America COMPETES Act of 2007 (P.L. 110-69), as amended by the America COMPETES Reauthorization Act of 2010 (P.L. 111-358), as further amended by the Energy Act of 2020 (P.L. 116-260): “(A) to enhance the economic and energy security of the United States through the development of energy technologies that— (i) reduce imports of energy from foreign sources; (ii) reduce energy-related emissions, including greenhouse gases; (iii) improve the energy efficiency of all economic sectors; (iv) provide transformative solutions to improve the management, clean-up, and disposal of radioactive waste and spent nuclear fuel; and (v) improve the resilience, reliability, and security of infrastructure to produce, deliver, and store energy; and (B) to ensure that the United States maintains a technological lead in developing and deploying advanced energy technologies.” ARPA-E issues this Funding Opportunity Announcement (FOA) under its authorizing statute codified at 42 U.S.C. § 16538. The FOA and any cooperative agreements or grants made under this FOA are subject to 2 C.F.R. Part 200 as supplemented by 2 C.F.R. Part 910. ARPA-E funds research on, and the development of, transformative science and technology solutions to address the energy and environmental missions of the Department. The agency focuses on technologies that can be meaningfully advanced with a modest investment over a defined period of time in order to catalyze the translation from scientific discovery to early-stage technology. For the latest news and information about ARPA-E, its programs and the research projects currently supported, see: http://arpa-e.energy.gov/. ARPA-E funds transformational research. Existing energy technologies generally progress on established “learning curves” where refinements to a technology and the economies of scale that accrue as manufacturing and distribution develop drive improvements to the cost/performance metric in a gradual fashion. This continual improvement of a technology is important to its increased commercial deployment and is appropriately the focus of the private sector or the applied technology offices within DOE. By contrast, ARPA-E supports transformative research that has the potential to create fundamentally new learning curves. ARPA-E technology projects typically start with cost/performance estimates well above the level of an incumbent technology. Given the high risk inherent in these projects, many will fail to progress, but some may succeed in generating a new learning curve with a projected cost/performance metric that is significantly better than that of the incumbent technology. ARPA-E funds technology with the potential to be disruptive in the marketplace. The mere creation of a new learning curve does not ensure market penetration. Rather, the ultimate value of a technology is determined by the marketplace, and impactful technologies ultimately become disruptive – that is, they are widely adopted and displace existing technologies from the marketplace or create entirely new markets. ARPA-E understands that definitive proof of market disruption takes time, particularly for energy technologies. Therefore, ARPA-E funds the development of technologies that, if technically successful, have clear disruptive potential, e.g., by demonstrating capability for manufacturing at competitive cost and deployment at scale. ARPA-E funds applied research and development. The Office of Management and Budget defines “applied research” as an “original investigation undertaken in order to acquire new knowledge…directed primarily towards a specific practical aim or objective” and defines “experimental development” as “creative and systematic work, drawing on knowledge gained from research and practical experience, which is directed at producing new products or processes or improving existing products or processes.” Applicants interested in receiving financial assistance for basic research (defined by the Office of Management and Budget as “experimental or theoretical work undertaken primarily to acquire new knowledge of the underlying foundations of phenomena and observable facts”) should contact the DOE’s Office of Science (http://science.energy.gov/). Office of Science national scientific user facilities (http://science.energy.gov/user-facilities/) are open to all researchers, including ARPA-E Applicants and awardees. These facilities provide advanced tools of modern science including accelerators, colliders, supercomputers, light sources and neutron sources, as well as facilities for studying the nanoworld, the environment, and the atmosphere. Projects focused on early-stage R&D for the improvement of technology along defined roadmaps may be more appropriate for support through the DOE applied energy offices including: the Office of Energy Efficiency and Renewable Energy (http://www.eere.energy.gov/), the Office of Fossil Energy and Carbon Management (https://www.energy.gov/fecm/office-fossil-energy-and-carbon-management), the Office of Nuclear Energy (http://www.energy.gov/ne/office-nuclear-energy), and the Office of Electricity (https://www.energy.gov/oe/office-electricity). Program Overview: GOPHURRS (Grid Overhaul with Proactive, High-Speed Undergrounding for Reliability, Resilience, and Security) intends to fund a portfolio of new technologies based on bold and unconventional ideas that will transform the construction of underground medium voltage (MV, 5 – 46 kV) power distribution grids (e.g., primary feeders and laterals) in urban and suburban areas and reduce the cost of undergrounding electric power grids by at least 50% in order to improve the overall reliability, resilience, and security of power infrastructure in the United States. SAIDI (System Average Interruption Duration Index) and SAIFI (System Average Interruption Frequency Index) are two commonly used reliability metrics. In the United States today, SAIDI and SAIFI range approximately 5-8 hours and 1.5 times per customer, respectively, which is responsible for an economic cost to U.S. electricity consumers of $79 billion/year. Undergrounding powerlines is a proven way of improving the system reliability for both transmission and distribution grids as indicated in stark differences in SAIDI and SAIFI of overhead systems and underground systems (Figure 1). Despite the reliability benefits, the cost of burying distribution powerlines is significant, up to five to ten times that of overhead distribution lines, making it the major barrier to making such grid investment decisions. Furthermore, today's undergrounding processes pose safety concerns, such as damage to other buried utilities during construction, occupational safety and health hazards associated with tasks performed in a manhole, and lengthy surface disruptions and traffic detours affecting the safety of surrounding communities, making undergrounding a difficult project to undertake. The GOPHURRS program aims to reduce the time and cost required to underground by a factor of at least two when compared to traditional trenching-based methods. More specifically, GOPHURRS technologies will shift the paradigm of undergrounding from digging to drilling in order to leave the surface nearly untouched. In order to achieve this goal, GOPHURRS focuses on developing transformative technologies capable of achieving autonomous/trenchless utility installation, such as automated and rapid subsurface drilling along the terrain and concurrent conduit installation, while also avoiding hidden underground obstacles (e.g., existing infrastructure, geologic anomalies) with advanced look-ahead sensors (Figure 2). In addition, GOPHURRS aims to reduce the life cycle cost of an underground power system by developing reliable cable joint designs and installation systems, as cable joints are typically the first to fail during operation. The GOPHURRS program could reduce costs, increase speed, and improve the reliability and safety of undergrounding operations and the surrounding communities by developing such technologies focused on automation, damage prevention, and error elimination. To view the FOA in its entirety, please visit https://arpa-e-foa.energy.gov.

The U.S. Department of State, Bureau of Political-Military Affairs, Office of Weapons Removal and Abatement (PM/WRA) is pleased to invite eligible organizations to submit applications for a cooperative agreement to conduct proliferation mitigation of Man-Portable Air Defense Systems (MANPADS) and Anti-Tank/All-purpose Tactical Guided Missiles (ATGMs) programming in and around Ukraine during fiscal year 2023. Specific goals, objectives, and technical requirements for application packages are detailed below. PM/WRA anticipates awarding up to $350,000 under this funding opportunity.

DE-FOA-0003048, SBIR/STTR Grid Overhaul with Proactive, High-speed Undergrounding for Reliability, Resilience, and Security (GOPHURRS) To obtain a copy of the Funding Opportunity Announcement (FOA) please go to the ARPA-E website at https://arpa-e-foa.energy.gov. To apply to this FOA, Applicants must register with and submit application materials through ARPA-E eXCHANGE (https://arpa-e-foa.energy.gov/Registration.aspx). For detailed guidance on using ARPA-E eXCHANGE, please refer to the ARPA-E eXCHANGE User Guide (https://arpa-e-foa.energy.gov/Manuals.aspx). ARPA-E will not review or consider concept papers submitted through other means. For problems with ARPA-E eXCHANGE, email ExchangeHelp@hq.doe.gov (with FOA name and number in the subject line). Questions about this FOA? Check the Frequently Asked Questions available at http://arpa-e.energy.gov/faq. For questions that have not already been answered, email ARPA-E-CO@hq.doe.gov. Agency Overview: The Advanced Research Projects Agency – Energy (ARPA-E), an organization within the Department of Energy (DOE), is chartered by Congress in the America COMPETES Act of 2007 (P.L. 110-69), as amended by the America COMPETES Reauthorization Act of 2010 (P.L. 111-358), as further amended by the Energy Act of 2020 (P.L. 116-260): “(A) to enhance the economic and energy security of the United States through the development of energy technologies that— (i) reduce imports of energy from foreign sources; (ii) reduce energy-related emissions, including greenhouse gases; (iii) improve the energy efficiency of all economic sectors; (iv) provide transformative solutions to improve the management, clean-up, and disposal of radioactive waste and spent nuclear fuel; and (v) improve the resilience, reliability, and security of infrastructure to produce, deliver, and store energy; and (B) to ensure that the United States maintains a technological lead in developing and deploying advanced energy technologies.” ARPA-E issues this Funding Opportunity Announcement (FOA) under its authorizing statute codified at 42 U.S.C. § 16538. The FOA and any cooperative agreements or grants made under this FOA are subject to 2 C.F.R. Part 200 as supplemented by 2 C.F.R. Part 910. ARPA-E funds research on, and the development of, transformative science and technology solutions to address the energy and environmental missions of the Department. The agency focuses on technologies that can be meaningfully advanced with a modest investment over a defined period of time in order to catalyze the translation from scientific discovery to early-stage technology. For the latest news and information about ARPA-E, its programs and the research projects currently supported, see: http://arpa-e.energy.gov/. ARPA-E funds transformational research. Existing energy technologies generally progress on established “learning curves” where refinements to a technology and the economies of scale that accrue as manufacturing and distribution develop drive improvements to the cost/performance metric in a gradual fashion. This continual improvement of a technology is important to its increased commercial deployment and is appropriately the focus of the private sector or the applied technology offices within DOE. By contrast, ARPA-E supports transformative research that has the potential to create fundamentally new learning curves. ARPA-E technology projects typically start with cost/performance estimates well above the level of an incumbent technology. Given the high risk inherent in these projects, many will fail to progress, but some may succeed in generating a new learning curve with a projected cost/performance metric that is significantly better than that of the incumbent technology. ARPA-E funds technology with the potential to be disruptive in the marketplace. The mere creation of a new learning curve does not ensure market penetration. Rather, the ultimate value of a technology is determined by the marketplace, and impactful technologies ultimately become disruptive – that is, they are widely adopted and displace existing technologies from the marketplace or create entirely new markets. ARPA-E understands that definitive proof of market disruption takes time, particularly for energy technologies. Therefore, ARPA-E funds the development of technologies that, if technically successful, have clear disruptive potential, e.g., by demonstrating capability for manufacturing at competitive cost and deployment at scale. ARPA-E funds applied research and development. The Office of Management and Budget defines “applied research” as an “original investigation undertaken in order to acquire new knowledge…directed primarily towards a specific practical aim or objective” and defines “experimental development” as “creative and systematic work, drawing on knowledge gained from research and practical experience, which is directed at producing new products or processes or improving existing products or processes.” Applicants interested in receiving financial assistance for basic research (defined by the Office of Management and Budget as “experimental or theoretical work undertaken primarily to acquire new knowledge of the underlying foundations of phenomena and observable facts”) should contact the DOE’s Office of Science (http://science.energy.gov/). Office of Science national scientific user facilities (http://science.energy.gov/user-facilities/) are open to all researchers, including ARPA-E Applicants and awardees. These facilities provide advanced tools of modern science including accelerators, colliders, supercomputers, light sources and neutron sources, as well as facilities for studying the nanoworld, the environment, and the atmosphere. Projects focused on early-stage R&D for the improvement of technology along defined roadmaps may be more appropriate for support through the DOE applied energy offices including: the Office of Energy Efficiency and Renewable Energy (http://www.eere.energy.gov/), the Office of Fossil Energy and Carbon Management (https://www.energy.gov/fecm/office-fossil-energy-and-carbon-management), the Office of Nuclear Energy (http://www.energy.gov/ne/office-nuclear-energy), and the Office of Electricity (https://www.energy.gov/oe/office-electricity). Program Overview: GOPHURRS (Grid Overhaul with Proactive, High-Speed Undergrounding for Reliability, Resilience, and Security) intends to fund a portfolio of new technologies based on bold and unconventional ideas that will transform the construction of underground medium voltage (MV, 5 – 46 kV) power distribution grids (e.g., primary feeders and laterals) in urban and suburban areas and reduce the cost of undergrounding electric power grids by at least 50% in order to improve the overall reliability, resilience, and security of power infrastructure in the United States. SAIDI (System Average Interruption Duration Index) and SAIFI (System Average Interruption Frequency Index) are two commonly used reliability metrics. In the United States today, SAIDI and SAIFI range approximately 5-8 hours and 1.5 times per customer, respectively, which is responsible for an economic cost to U.S. electricity consumers of $79 billion/year. Undergrounding powerlines is a proven way of improving the system reliability for both transmission and distribution grids as indicated in stark differences in SAIDI and SAIFI of overhead systems and underground systems (Figure 1). Despite the reliability benefits, the cost of burying distribution powerlines is significant, up to five to ten times that of overhead distribution lines, making it the major barrier to making such grid investment decisions. Furthermore, today's undergrounding processes pose safety concerns, such as damage to other buried utilities during construction, occupational safety and health hazards associated with tasks performed in a manhole, and lengthy surface disruptions and traffic detours affecting the safety of surrounding communities, making undergrounding a difficult project to undertake. The GOPHURRS program aims to reduce the time and cost required to underground by a factor of at least two when compared to traditional trenching-based methods. More specifically, GOPHURRS technologies will shift the paradigm of undergrounding from digging to drilling in order to leave the surface nearly untouched. In order to achieve this goal, GOPHURRS focuses on developing transformative technologies capable of achieving autonomous/trenchless utility installation, such as automated and rapid subsurface drilling along the terrain and concurrent conduit installation, while also avoiding hidden underground obstacles (e.g., existing infrastructure, geologic anomalies) with advanced look-ahead sensors (Figure 2). In addition, GOPHURRS aims to reduce the life cycle cost of an underground power system by developing reliable cable joint designs and installation systems, as cable joints are typically the first to fail during operation. The GOPHURRS program could reduce costs, increase speed, and improve the reliability and safety of undergrounding operations and the surrounding communities by developing such technologies focused on automation, damage prevention, and error elimination. To view the FOA in its entirety, please visit https://arpa-e-foa.energy.gov.

While media in the Kyrgyz Republic is the most open in the region, few outlets are truly independent and the industry suffers from self-censorship, a lack of professionalism, and financial sustainability issues. Misinformation and disinformation are regularly disseminated by both local and international actors through local media. Independent media outlets have been subjected to harassment, threats, and unfounded defamation lawsuits by subjects of reporting. The Media Small Grants Program advances the U.S. Embassy goal of supporting a more inclusive and accountable democracy. It seeks to expand the capabilities of independent media, resulting in increased production of balanced and locally relevant media products as well as diverse and alternative media narratives. The program also supports the development of the Kyrgyz Republic’s nonprofit, nongovernmental organizations (NGOs), and associations working in the media-related areas. Through local innovative strategies, the program may address policy priorities such as: Promoting freedom of speech and press. Increasing journalistic professionalism and sustainability of independent media organizations. Fostering government transparency and advocacy and fighting corruption. Informing the public regarding the work and contributions of civil society organizations to the Kyrgyz Republic’s social and economic development. Raising public awareness and participation in efforts to combat climate change and air pollution. Raising public awareness of and increasing resiliency to misinformation and disinformation.

Amendment 2 to the NASA ARMD Research Opportunities in Aeronautics (ROA) 2023 NRA has been posted on the NSPIRES web site.NASA Aeronautics recognizes that to develop the new air transportation ecosystem, it has to focus not just on the new forms of aircraft but also on the wider system in which these aircraft will operate. This program element focuses on one of the prominent issues likely to be faced by the future air transportation industry – Aviation Maintenance. It is important to identify the new and unique maintenance issues that will crop up with these new forms of air transportation and also develop the workforce for it.Research proposals are sought to address key maintenance and training challenges facing the next-generation of air transportation in Appendix D.6. Notices of Intent (NOIs) are encouraged, although not required, to be submitted by April 21, 2023. An Applicant’s Workshop will be held on Wednesday April 26, 2023; 1:00-2:00 p.m. ET. The meeting link will be posted on NSPIRES. Proposals are due May 31, 2023, 5 pm ET.

The Department of Veterans Affairs (VA) National Cemetery Administration (NCA) is awarding grants for a maximum of $500,000 per awardee through the Veterans Legacy Grants Program (VLGP), authorized under 38 U.S.C. 2400 note to provide funding to educational institutions and other eligible entities to conduct cemetery research and produce educational tools for the public to utilize and learn about the histories of Veterans interred in VA national cemeteries and VA grant-funded State and Tribal Veterans’ cemeteries. This notice includes information about the process for applying for a VLGP grant; criteria for evaluating applications; priorities related to the award of grants; and other requirements and guidance regarding VLGP grants.